Table 3.
K-D Cut Scores for Distinguishing Controls from MCI
| K-D Score | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
| 48 | 92.3 | 17.0 | 24.3 | 88.5 |
| 50 | 89.7 | 26.7 | 26.1 | 90.0 |
| 52 | 89.7 | 34.1 | 28.2 | 92.0 |
| 54 | 84.6 | 39.3 | 28.7 | 89.8 |
| 56 | 84.6 | 45.9 | 31.1 | 91.2 |
Presented cutoffs represent those with a sensitivity ≥80 to be consistent with the nature of screening instruments that favor high sensitivity and sacrifice specificity. The prevalence used for calculation of PPV and NPV is based on the in sample prevalence of MCI.
Abbreviations: K-D = King-Devick; MCI = mild cognitive impairment; PPV = positive predictive value; NPV = negative predictive value