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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Int J Antimicrob Agents. 2016 Nov 2;48(6):690–694. doi: 10.1016/j.ijantimicag.2016.09.020

Fig. 3.

Fig. 3

Activity of auranofin (AF) against trichomonads in vitro. The activity of AF, with and without added H2O2, against the indicated strains of Trichomonas vaginalis and Tritrichomonas foetus was evaluated in a 24-h growth and survival assay using ATP as a read-out. Results in (A) and (C) are expressed as percentage of surviving cells compared with untreated controls, while 50% inhibitory concentration (IC50) values in (B) were calculated by graphic extrapolation from concentration–response curves. Metronidazole (MZ) IC50 values against T. vaginalis are shown in (B) for comparison. In all three panels, data are the mean ± standard error of the mean (n = 3). * P < 0.05 vs. untreated cells (t-test).