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. Author manuscript; available in PMC: 2018 Jan 6.
Published in final edited form as: Neuroscience. 2016 Nov 2;340:243–257. doi: 10.1016/j.neuroscience.2016.10.062

Figure 6. GNX-induced social interaction impairments were prevented by mPFC Zif268 reinstitution.

Figure 6

Frequency of social interactions was unaffected by GNX or by AAV-Zif268 treatment (A). Time spent engaging in social interaction was significantly reduced in GNX/Control animals as compared to GNX/Zif268 counterparts, with a trend towards a reduction versus intact controls (B). Neither GNX nor AAV-Zif268 treatment influenced the frequency (C) or duration (D) of anogenital investigation in the social interaction test. Data are presented as means ± SEM. *p<0.05 versus GNX/Zif268, n=6/group.