Table 2.
Empirical type I error of LSKAT and LBT without modeling the individual-level time-dependent correlation, based on 106 simulated replicates. Rates that are significantly larger than the nominal levels are in bold.
| Sample Size | Empirical Type I Error | |||||
|---|---|---|---|---|---|---|
| LSKAT | LBT | |||||
| α = 10−3 | α = 10−4 | α = 10−5 | α = 10−3 | α = 10−4 | α = 10−5 | |
| 500 | 9.3 × 10−4 | 8.2 × 10−5 | 8 × 10−6 | 1.0 × 10−3 | 9.5 × 10−5 | 7 × 10−6 |
| 1000 | 1.0 × 10−3 | 7.9 × 10−5 | 7 × 10−6 | 1.1 × 10−3 | 1.1 × 10−4 | 8 × 10−6 |
| 2500 | 1.5 × 10−3 | 2.7 × 10−4 | 4.3 × 10−5 | 1.7 × 10−3 | 3.0 × 10−4 | 5.7 × 10−5 |