Figure 5.
SRAP expression in normal development of P. miniata. To determine the temporal expression of the SRAP transcript in Pm, an RNA probe was synthesized for in situ hybridization and a probe against the neomycin-resistance gene was used as a negative control (A). The expression was tested in immature (a) and mature (b) oocytes, blastula (c), mid (d) and late gastrula (e), 4 day larva (f), and 6 day larva (g). The strongest expression was detected in the stomach of the larvae. qPCR was used to measure the RNA levels of SRAP at the indicated developmental stages: immature oocytes, hatched blastula, mid and late gastrula, 3 day, 4 day and 7 day old larvae (B). All values were normalized against the 18S mRNA and represented as a fold-change relative the amount of RNA present in hatched blastula.
