Figure 2. Δ%C (mean ± standard error) as a function of KCl concentration for (A) controls and (B–E) following various levels and rates of axial overstretch.

Controls show changes in contractility with repeated exposures to identical dosing sequences. Comparison of overstretch and control groups shows that the ability of vessels to contract tends to be impaired following higher, faster overstretch. “*” indicates statistical difference from the time-matched control group measurement.