. Author manuscript; available in PMC: 2018 Jan 1.

Published in final edited form as: Genet Epidemiol. 2016 Nov 10;41(1):70–80. doi: 10.1002/gepi.22018

Table 1.

Impact of different number of latent factors K and different SNR levels on Regulator Selection and Group Selection

			Regulator Selection			Group Selection
SNR	K _true	Method	TF	Sen	MCC	TF	Sen	MCC
Simulation I.1
1:0:3	0	smFARM_K=0	18.90(6.02)	0.89(0.04)	0.92(0.02)	0.06(0.24)	1(0)	0.99(0.02)
		remMap	21.88(6.61)	0.93(0.02)	0.92(0.02)	0.02(0.14)	1(0)	1(0.01)
1:0:5	0	smFARM_K=0	27.24(3.51)	0.81(0.03)	0.88(0.01)	0(0)	1(0)	1(0)
		remMap	34.10(5.17)	0.88(0.03)	0.87(0.02)	0(0)	1(0)	1(0)
Simulation I.2
1:1:3	2	smFARM_K=2	18.24(3.46)	0.87(0.03)	0.92(0.01)	0(0)	1(0)	1(0)
		remMap	25.68(11.32)	0.83(0.04)	0.89(0.04)	0.02(0.14)	1(0)	1(0.01)
1:1:5	2	smFARM_K=2	28.51(4.26)	0.80(0.03)	0.88(0.02)	0(0)	1(0)	1(0)
		remMap	33.40(4.92)	0.76(0.04)	0.86(0.02)	0(0)	1(0)	1(0)

Simulation II
1:3:5	2	smFARM_K=2	48.89(11.54)	0.82(0.05)	0.87(0.03)	10.89(2.53)	0.66(0.06)	0.79(0.05)
		smFARM_K=0	79.80(16.76)	0.77(0.02)	0.79(0.04)	12.10(1.25)	0.62(0.04)	0.76(0.03)
		remMap	87.46(20.67)	0.79(0.03)	0.77(0.05)	12.46(1.35)	0.62(0.05)	0.75(0.03)

Note:For each Total False (TF), Sensitivity (Sen), or Matthews correlation coefficient (MCC) measurement, we report mean values together with their standard errors on 50 replicates. smFARM_K=K₀ represents fitting the smFARM on a given number of latent factors K₀.