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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Brain Behav Immun. 2016 Aug 31;59:147–157. doi: 10.1016/j.bbi.2016.08.019

Figure 3. Effects of stress and resveratrol treatment on splenic TNFα levels 5 days post social defeat or control exposure.

Figure 3

RSV decreased expression of the pro-inflammatory cytokine TNFα following Con-A stimulation in splenic cells of passive coping rats. Data are expressed as the percentage of total CD4+ cells expressing TNFα. (A, B, C) Data shown are flow cytometry dot plots from one representative animal in each group shown. (D) Graph of combined data from all experiments (n=8 [control + vehicle]; n=7 [passive + vehicle]; n=8 [active + vehicle]; n=5 [control + 10mg/kg RSV]; n=8 [passive + 10mg/kg RSV]; n=4 [active + 10mg/kg RSV]; n=5 [control + 30mg/kg RSV]; n=9 [passive + 30mg/kg RSV]; n=4 [active + 30mg/kg RSV]). Fisher’s LSD post-hoc analysis revealed statistical significance (ƒ p<0.0001 vs. control + vehicle; * p<0.0001 vs. active + vehicle; ** p<0.0001 vs. passive + vehicle).