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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: J Mol Cell Cardiol. 2016 Oct 11;101:35–43. doi: 10.1016/j.yjmcc.2016.10.004

Figure 3. Canonical scheme for Ca2+/CaM-dependent activation of myosin light chain kinase (MLCK) and phosphorylation of myosin RLC.

Figure 3

Ca2+/CaM-dependent MLCKs are inactive until bound to Ca2+/CaM, leading to phosphorylation of myosin RLC. Phosphorylated myosin RLC is dephosphorylated by myosin light chain phosphatases (MLCP).