Figure 4.

Nlrp2 is dispensable for parthenogenetic development of oocytes from young adult mice. (a) Representative bright field micrographs of developing embryos at days 1, 2, 3, and 5 after parthenogenetic activation of oocytes obtained from 6–10-wk-old WT and Nlrp2^−/− mice. (b) Fraction of activated oocytes from 6–10 wk old WT and Nlrp2^−/− mice that reached the indicated embryonic cleavage stages. (c) Kinetic analysis of the progression of activated oocytes from 6–10-wk-old WT and Nlrp2^−/− mice through the indicated embryonic cleavage stages. Data represent mean ± SD of 201 oocytes from 16 WT mice, and 297 oocytes from 16 Nlrp2^−/− mice. (ns, nonsignificant; Student’s t test). Bars, 50 µm.