Figure 7. Immunoblot analysis of subcellular fractions isolated from fly lines expressing different dPrx5 forms.
dPrx5 protein expression from different UAS transgenes was assessed in the dprx5 null background. Genotypes of fly lines were as follows: cytosolic – UAS-cyt dPrx5/+; Da-GAL4, dprx5/dprx5; nuclear – UAS-nucl dPrx5/+; Da-GAL4, dprx5/dprx5; mitochondrial – UAS-mit dPrx5/+; Da-GAL4, dprx5/dprx5. For each form, three independent fly lines were generated and immunoblot analysis was performed in triplicate. Flies expressing the endogenous dPrx5 protein served as a positive control (C). Antibodies raised to compartment-specific proteins (GCLm, Histone H3 and dPrx3) were used to control for loading and purity of subcellular fractions.
