Table 3.

Mean life span of DM female flies expressing different forms of dPrx5 from transgene

Normal conditions
Fly Lines	Mean, days	% vs Control	p value	% vs DM	p value
Control	44.5			+68.54	<0.0001
	55			+76.36	<0.0001
dPrx5	39	−12.36	<0.0001	+64.10	<0.0001
	35	−36.36	<0.0001	+62.86	<0.0001
Cyt	14	−68.54	<0.0001	0	0.3707
	14	−74.55	<0.0001	+7.14	<0.0001
Nucl	14	−68.54	<0.0001	0	0.4957
	14	−74.55	<0.0001	+7.14	<0.0001
Mit	23	−48.31	<0.0001	+39.13	<0.0001
	23	−58.18	<0.0001	+43.48	<0.0001
DM	14	−68.54	<0.0001
	13	−76.36	<0.0001
Hydrogen peroxide
Genotype	Mean, hours	% vs Control	P value	% vs DM	P value
Control	114			+45.61	<0.0001
	141			+47.52	<0.0001
dPrx5	85	−25.44	<0.0001	+27.06	<0.0001
	92	−34.75	<0.0001	+19.57	<0.0001
Cyt	73	−35.96	<0.0001	+15.07	<0.0001
	83	−41.13	<0.0001	+10.84	0.5718
Nucl	62	−45.61	<0.0001	0	0.6329
	67	−52.48	<0.0001	−9.46	0.0085
Mit	85	−25.44	<0.0001	+27.06	<0.0001
	97	−31.21	<0.0001	+23.71	<0.0001
DM	62	−45.61	<0.0001
	74	−47.52	<0.0001
Paraquat
Control	266		<0.0001	+66.54	<0.0001
	249		<0.0001	+54.22	<0.0001
dPrx5	179	−32.71	<0.0001	+50.28	<0.0001
	163	−34.54	<0.0001	+30.06	<0.0001
Cyt	89	−66.54	<0.0001	0	0.0643
	63	−74.70	<0.0001	−44.74	<0.0001
Nucl	112	−57.89	<0.0001	+20.54	0.2107
	114	−54.22	<0.0001	0	0.6203
Mit	179	−32.71	<0.0001	+50.28	<0.0001
	131	−47.39	<0.0001	+12.98	0.0119
DM	89	−66.54	<0.0001
	114	−54.22	<0.0001

Life span data in column 2 are mean life span of the groups shown in Fig.8. Column 3 and 4 indicate the percent changes in experimental groups vs control (Da-GAL4, dprx5/+), and the significance probabilities (p values) of the associated log rank tests. Similarly, columns 5 and 6 indicate percent changes and p values in relation to DM (Da-GAL4, dprx5/ RNAi-dprx3, dprx5). Genotypes of fly lines are shown in Table 1.