Table 4.

Mean life span of DM male flies expressing different forms of dPrx5 from transgene

Normal conditions
Fly Lines	Mean, days	% vs Control	p value	% vs DM	p value
Control	51.00			+62.72	<0.0001
	49.00			+55.10	<0.0001
dPrx5	44.50	−12.75	<0.0001	+57.30	<0.0001
	47.00	−4.08	<0.0001	+53.19	<0.0001
Cyt	18.00	−64.71	<0.0001	−5.26	0.3664
	23.00	−53.06	<0.0001	+4.35	0.2983
Nucl	19.00	−62.75	<0.0001	0	0.4218
	20.00	−59.18	<0.0001	−9.09	0.0063
Mit	29.00	−43.14	<0.0001	+34.48	<0.0001
	27.00	−44.89	<0.0001	+18.52	<0.0001
DM	19.00	−62.75	<0.0001
	22.00	−55.10	<0.0001
Hydrogen peroxide
Genotype	Mean, hours	% vs Control	P value	% vs DM	P value
Control	92.00			+27.17	<0.0001
	85.00			+27.06	<0.0001
dPrx5	67.00	−27.17	<0.0001	0	<0.0001
	62.00	−27.06	<0.0001	0	0.3336
Cyt	67.00	−27.17	<0.0001	0	0.4578
	62.00	−27.06	<0.0001	0	0.0124
Nucl	67.00	−27.17	<0.0001	0	<0.0001
	62.00	−27.06	<0.0001	0	0.0040
Mit	70.00	−23.91	<0.0001	+4.29	0.0254
	67.00	−21.18	<0.0001	+7.46	0.0007
DM	67.00	−27.17	<0.0001
	62.00	−27.06	<0.0001
Paraquat
Control	200			+34.50	<0.0001
	199			+26.63	<0.0001
dPrx5	131	−34.50	<0.0001	0	<0.0001
	146	−26.63	<0.0001	0	0.1438
Cyt	119	−40.50	<0.0001	−9.16	0.2122
	146	−26.63	<0.0001	0	0.8483
Nucl	153	−23.50	<0.0001	+14.38	<0.0001
	112	−43.71	<0.0001	−23.29	<0.0001
Mit	131	−34.50	<0.0001	0	<0.0001
	168	−15.58	<0.0001	+13.10	<0.0001
DM	131	−34.50	<0.0001
	146	−26.63	<0.0001

Life span data in column 2 are mean life span of the groups shown in Fig.8. Column 3 and 4 indicate the percent changes in experimental groups vs control (Da-GAL4, dprx5/+), and the significance probabilities (p values) of the associated log rank tests. Similarly, columns 5 and 6 indicate percent changes and p values in relation to DM (Da-GAL4, dprx5/ RNAi-dprx3, dprx5). Genotypes of fly lines are shown in Table 1.