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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Gynecol Oncol. 2016 Mar 11;141(2):348–356. doi: 10.1016/j.ygyno.2016.02.030

Figure 1. TCGA in silico analysis.

Figure 1

Figure 1A shows the heat map of nuclear receptor expression for tumors in the TCGA. Columns within the heat map represent TCGA tumor samples and rows represent individual nuclear receptors. The tight clustering algorithm utilized grouped the tumors into 5 clusters (see methods). Figure 1B shows progression-free and overall survival for the subset of patients with NR4A overexpression (cluster 1) as compared to those patients with lower NR4A expression. Median progression free survival of cluster 1 patients is significantly worse than that for those patients in clusters 2–5 (p=0.03). While there was a trend towards worse overall survival for those patients in cluster 1, the results did not reach statistical significance (p=0.09).