Figure 2.
Paclitaxel release from PLA microfibers can be controlled and tuned based on the original loading level of paclitaxel. PLA microfibers were placed in PBS and aliquots were analyzed by HPLC over 84 days and the cumulative (A) and fraction (B) release were calculated. As the initial loading of paclitaxel increased, the release rate increased, and the fraction released increased at a slower rate than fibers with a lower incorporation of paclitaxel.
