Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A blocking of microtubule stabilization ablates the neurite extension from paclitaxel. To ensure that this paclitaxel delivery mechanism maintains neurite extension via microtubule stabilization nocodazole, a microtubule-destabilizing agent, was added to DRG neurons cultured on PLA microfibers loaded with or without paclitaxel. Once this microtubule stabilization is blocked, the previous axonal extension due to the local release of paclitaxel no longer occurs (n = 3 – 6).
