Table 1. The summary of significant overexpression and underexpression genes which were differently expressed in MUM-2B suppressed by CTLs activated by DCs.
Significant overexpressed genes |
Significant underexpressed genes |
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Probe Set ID | Entrez gene | Gene symbol | Fold change | P | Probe Set ID | Entrez gene | Gene symbol | Fold change | P | |
Antigen processing and presentation | ||||||||||
TC01001382.hg.1 | 2207 | FCER1G | 125.13 | 0 | ||||||
TC17001466.hg.1 | 1236 | CCR7 | 7.15 | 0 | ||||||
TC19000174.hg.1 | 3383 | ICAM1 | 10.7 | 0 | ||||||
TC03001629.hg.1 | 961 | CD47 | 2.32 | 0 | ||||||
TC05001936.hg.1 | 972 | CD74 | 30.85 | 0 | ||||||
Response to stress | ||||||||||
TC01001372.hg.1 | 57823 | SLAMF7 | 184.97 | 0.02 | TC01002166.hg.1 | 54206 | ERRFI1 | -6.44 | 0 | |
TC06000371.hg.1 | 7124 | TNF | 6.4 | 0 | TC01006383.hg.1 | 4582 | MUC1 | -6.59 | 0 | |
TC09000035.hg.1 | 3717 | JAK2 | 6.86 | 0 | TC05000701.hg.1 | 1958 | EGR1 | -7.43 | 0 | |
TC14000133.hg.1 | 4323 | MMP14 | 14.06 | 0 | TC17001472.hg.1 | 3858 | KRT10 | -36.96 | 0 | |
TC08000305.hg.1 | 3620 | IDO1 | 5.23 | 0 | TC10000715.hg.1 | 1244 | ABCC2 | -17.81 | 0 | |
TC15000441.hg.1 | 366 | AQP9 | 132.24 | 0 | ||||||
Inflammatory response | ||||||||||
TC03001355.hg.1 | 1230 | CCR1 | 20.07 | 0 | TC19000458.hg.1 | 5349 | FXYD3 | -22.76 | 0 | |
TC16000487.hg.1 | 6367 | CCL22 | 136.23 | 0 | ||||||
TC17000406.hg.1 | 6362 | CCL18 | 25.84 | 0 | ||||||
TC04000408.hg.1 | 3576 | IL8 | 47.89 | 0 | ||||||
TC02000937.hg.1 | 7130 | TNFAIP6 | 93.09 | 0 | ||||||
TC07000687.hg.1 | 5294 | PIK3CG | 32.25 | 0 | ||||||
TC10001559.hg.1 | 118788 | PIK3AP1 | 20.88 | 0 | ||||||
TC12000611.hg.1 | 4069 | LYZ | 494.38 | 0 | ||||||
T cell mediated cytotoxicity and T cell activation | ||||||||||
TC05002050.hg.1 | 3937 | LCP2 | 14.72 | 0 | TC05000372.hg.1 | 2150 | F2RL1 | -6.55 | 0 | |
TC13000642.hg.1 | 3936 | LCP1 | 20.3 | 0 | TC15001471.hg.1 | 4734 | NEDD4 | -6.6 | 0 | |
TC01003006.hg.1 | 26191 | PTPN22 | 26.56 | 0 | ||||||
TC12000955.hg.1 | 5027 | P2RX7 | 27.82 | 0 | ||||||
TC01003407.hg.1 | 8832 | CD84 | 30.89 | 0 | ||||||
TC01001640.hg.1 | 5788 | PTPRC | 65.05 | 0 | ||||||
TC16000349.hg.1 | 3683 | ITGAL | 18.59 | 0 | ||||||
TC19000174.hg.1 | 3383 | ICAM1 | 10.7 | 0 | ||||||
Natural killer cell mediated cytotoxicity | ||||||||||
TC01001372.hg.1 | 57823 | SLAMF7 | 184.97 | 0.02 | TC06002224.hg.1 | 79465 | ULBP3 | -8.53 | 0.02 | |
TC12000101.hg.1 | 5777 | PTPN6 | 9.51 | 0.02 | ||||||
TC01003996.hg.1 | 1130 | LYST | 5.46 | 0.02 |