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Small changes in model parameters change the predicted response to L-type Ca2+ or NaV channel blockers. A1: ḡNa = 10,003 mS/cm2, ḡCa = 0.15 mS/cm2. A2: ḡNa = 10,003 mS/cm2, ḡCa = 0 mS/cm2. B1: ḡNa = 10,002 mS/cm2, ḡCa = 0.15 mS/cm2. B2: ḡNa = 10,002 mS/cm2, ḡCa = 0 mS/cm2. [Adapted from Drion et al. (2011).]
