Table 8.
PGEM and PGFM in fetuses.
| Groups | PGEM (pg/mg of protein) | PGFM (pg/mg of protein) | ||
|---|---|---|---|---|
| Fetuses | ||||
| Vehicle-treated control (V-TC) (n = 69) | 133.11 ± 13.56 | 132.56 ± 12.51 | ||
| LA-treated control (LA-TC) (n = 61) | 113.51 ± 8.28 | 120.06 ± 8.92 | ||
| Nonmalformed†∗ | Malformed† | Nonmalformed | Malformed | |
| Vehicle-treated diabetic (V-TD) (n = 48) | 92.64 ± 6.95 | 67.33 ± 2.71 | 109.24 ± 10.84 | 159.54 ± 8.97∗∗∗ |
| LA-treated diabetic (LA-TD) (n = 59) | 109.35 ± 8.38 | 75.23 ± 3.32∗∗ | 115.14 ± 7.05 | 155.80 ± 9.40∗∗∗ |
†Significantly lower (p < 0.05) than those in both controls.
∗Significantly higher (p < 0.05) than those in the malformed fetuses of both groups of diabetic rats.
∗∗Significantly higher (p < 0.05) than those in malformed fetuses from V-TD rats.
∗∗∗Significantly higher (p < 0.05) than those in nonmalformed fetuses of V-TD, LA-TD, and both groups of control rats.