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Molar ratio composition of QF-NIC coamorphous dispersions.
| Formula number | Drug (mg) | Nicotinamide (mg) | ∗∗Mr | Solvent system | Evaporation method |
|---|---|---|---|---|---|
| F1 | 150 | 41.49 | 1 : 1 | Ethanol | Cold evap. |
| F2 | 150 | 41.49 | 1 : 1 | ∗Eth/W | Cold evap. |
| F3 | 150 | 82.98 | 1 : 2 | Ethanol | Cold evap. |
| F4 | 150 | 82.98 | 1 : 2 | ∗Eth/W | Cold evap. |
| F5 | 150 | 124.47 | 1 : 3 | Ethanol | Cold evap. |
| F6 | 150 | 124.47 | 1 : 3 | ∗Eth/W | Cold evap. |
∗: Eth/W: ethanol/water system 50 : 50 v/v; ∗∗Mr: molar ratio.
