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Results of in vitro gut permeation of QF through duodenum and jejunum compared to the coamorphous dispersion F6.
| Formula | Duodenum | Jejunum | ||||
|---|---|---|---|---|---|---|
| Flux rate (mg/cm2/h) |
Lag time (min) |
Regression R 2 |
Flux rate (mg/cm2/h) |
Lag time (min) |
Regression R 2 |
|
| Pure QF | 0.027 | 38.22 | 0.97 | 0.028 | 32.51 | 0.98 |
| QF-NIC (F6) | 0.041 | 12.15 | 0.99 | 0.036 | 17.72 | 0.99 |
