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. 2016 Dec 8;7:13803. doi: 10.1038/ncomms13803

Figure 3. CpaA is a novel capreomycin acetyltransferase.

Figure 3

(a) CpaA specifically modifies capreomycin. A spectrophotometric assay was used to monitor acetylation of capreomycin, viomycin or kanamycin by CpaA. (b) Structure of capreomycin highlighting the site of CpaA acetylation. Arrows and bold bonds represent important correlations in multi-dimensional NMR experiments. Arrows represent important multi-bond heteronuclear multiple-bond correlation spectroscopy (HMBC) correlations and bold bonds represent multi-bond total correlation spectroscopy (TOCSY) and heteronuclear single-quantum correlation spectroscopy (HSQC) correlations.