Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Dec 8;7:13557. doi: 10.1038/ncomms13557

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) One edge of the previously identified gp42 HP interacts with gH D-II. The gp42 C-domain surface is coloured hotpink, with HP residues shown in slate (shade of blue) and labelled. The gH D-II is shown as a cartoon and coloured wheat. Gp42 residues gp42:I187, gp42:F188 and gp42:F210 interact with gH D-II. (b) Two gp42 histidines (gp42:H205 and gp42:H206, cyan sticks) in the HP form contacts with gH:E282 (orange). HP residues not directly in contact with gH are indicated by their Cα atom shown as spheres. (c) gp42:L85 (sticks) contacts gH:G189 in the ¹⁸⁸KGD¹⁹⁰ motif, while gp42:E171 (cyan) is positioned to form charge–charge interactions with gH:K188. The shortest distance (10.4 Å) between the minimal inhibitory peptide of gp42 peptide ending at gp42:W81 (ref. ¹⁷) with the gH ¹⁸⁸KGD¹⁹⁰ motif is highlighted. Structures were rendered using MacPyMol.