Table 3. Open-field test.

Age	P24		P87
Behavior/groups	Tactile	Needle	Tactile	Needle
Inner time (s)	10.55 ± 3.36	20.35 ± 3.48#	9.46 ± 1.84	15.61 ± 2.10*
Outer time (s)	587.70 ± 3.38	578.60 ± 3.39	590.18 ± 1.84	583.23 ± 2.06*
Inner distance (%)	5.64 ± 0.99	8.53 ± 0.83*	2.68 ± 0.54	5.06 ± 0.64**
Total distance (mm)	11299.44 ± 915.05	12975.77 ± 702.44	13465.64 ± 712.51	15371.12 ± 724.98
Inner crossing (%)	34.42 ± 3.44	45.02 ± 1.38**	41.64 ± 2.65	46.3 ± 1.14
Total crossing (n)	15.20 ± 2.43	19.35 ± 1.95	11.06 ± 1.83	19.78 ± 2.59*

Data are expressed as mean ± SEM. Student-t test was used to compare the group difference, *P < 0.05, **P < 0.01, ^#P = 0.05 for Needle vs. Tactile (n = 10), n = number of occurrences.