Table 1. KEGG pathway showing significant changes in C. beijerinckii DG-8052 cultures with addition of 4 g/L CaCO3.
| culture | KEGG ID | Pathway definition | p value | Benjamini* | Count** |
|---|---|---|---|---|---|
| Up-regulated | |||||
| 12 h | cbe02010 | ABC transporters | 1.8E-3 | 1.0E-1 | 30 |
| cbe00562 | Inositol phosphate metabolism | 2.4E-3 | 7.2E-2 | 5 | |
| cbe00400 | Phenylalanine, tyrosine and tryptophan biosynthesis | 2.5E-3 | 5.0E-2 | 9 | |
| cbe02020 | Two-component system | 4.2E-2 | 6.2E-2 | 16 | |
| cbe00620 | Pyruvate metabolism | 4.0E-2 | 3.9E-2 | 10 | |
| 24 h | cbe00040 | Pentose and glucuronate interconversions | 9.4E-8 | 6.3E-6 | 20 |
| cbe02020 | Two-component system | 5.6E-4 | 1.9E-2 | 24 | |
| cbe00400 | Phenylalanine, tyrosine and tryptophan biosynthesis | 1.0E-3 | 2.3E-2 | 12 | |
| cbe00030 | Pentose phosphate pathway | 8.1E-3 | 1.3E-1 | 16 | |
| cbe00450 | Selenoamino acid metabolism | 9.1E-3 | 1.1E-1 | 8 | |
| cbe02010 | ABC transporters | 1.0E-2 | 1.1E-1 | 40 | |
| cbe00562 | Inositol phosphate metabolism | 1.5E-2 | 1.3E-1 | 5 | |
| cbe00290 | Valine, Leucine and isoleucine biosynthesis | 3.4E-2 | 2.5E-1 | 9 | |
| cbe00480 | Glutathione metabolism | 6.6E-2 | 3.1E-1 | 5 | |
| cbe00620 | Pyruvate metabolism | 6.6E-2 | 3.7E-1 | 13 | |
| cbe00020 | Citrate cycle (TCA cycle) | 7.6E-2 | 3.8E-1 | 5 | |
| Down-regulated | |||||
| 12 h | cbe00190 | Oxidative phosphorylation | 5.2E-4 | 2.8E-2 | 10 |
| cbe00330 | Arginine and proline metabolism | 7.5E-4 | 2.0E-2 | 11 | |
| cbe00440 | Phosphonate and phosphinate metabolism | 1.1E-2 | 1.8E-1 | 4 | |
| cbe00250 | Alanine, aspartate and glutamate metabolism | 6.5E-2 | 6.0E-1 | 7 | |
| cbe00230 | Purine metabolism | 9.0E-2 | 6.5E-1 | 11 | |
| 24 h | cbe00440 | Phosphonate and phosphinate metabolism | 4.0E-3 | 1.3E-1 | 5 |
| cbe00730 | Thiamine metabolism | 1.7E-3 | 1.1E-1 | 9 | |
| cbe00860 | Porphyrin and chlorophyll metabolism | 6.3E-3 | 1.4E-1 | 11 | |
| cbe00330 | Arginine and proline metabolism | 2.6E-2 | 3.7E-1 | 11 | |
| cbe00190 | Oxidative phosphorylation | 4.5E-2 | 4.7E-1 | 9 | |
*Significant groups were selected based upon Benjamini (<0.05).
**Number of genes within the given KEGG ID showing a significant change in their expression level.