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. 2016 Nov 10;115(12):1548–1554. doi: 10.1038/bjc.2016.367

Figure 2.

Figure 2

The prediction and validation of miR-146a-5p target gene. (A) Notch2 exhibits miR-146a-5p-binding sequences in its 3′-UTR regions. (B) Luciferase assays validated that Notch2 is a target of miR-146a-5p. (C, D) Further evidence of miR-146a-5p targeting Notch2 by western blotting. **P<0.01; ***P<0.001.