Table 2. Composition of 3-GPS.
| Signaturea | REOs (Ga>Gb)b | βc | Pd | C-index |
|---|---|---|---|---|
| Gene pair 1 | LOC81691>ZMYND10 | −5.56 | 0.0133 | 0.80 |
| Gene pair 2 | TREM1>ANPEP | −2.43 | 0.0450 | 0.79 |
| Gene pair 3 | ERN1>FA2H | −3.95 | 0.0213 | 0.77 |
a
Predictive model: a sample was determined to be responder if any two of the three gene pairs with the specific REOs (Ga>Gb); otherwise, the non-responder.
b
Represents the REO (Ga>Gb) more frequently occur in the pCR group than in the pNR; The statistics are calculated from multivariate Cox regression model.
c
β represents risk coefficient of REO (Ga>Gb).
d
P represents the significance of the correlation between the REO (Ga>Gb) and 5-year survival rate.