Table 2. Metabolites in liver of Merino, Dorper and Damara sheep breeds, with significant differences between growth and restricted groups, in at least one breed.
Merino |
Dorper |
Damara |
||||
---|---|---|---|---|---|---|
growth | restricted | growth | restricted | growth | restricted | |
3-Hydroxybutyrate | 3.3 E-04 ± 1.0 E-04 | 4.7 E-04* ± 1.4 E-04 | 2.4 E-04 ± 10.0 E-05 | 3.2 E-04 ± 1.4 E-04 | 2.9 E-04 ± 7.9 E-05 | 2.7 E-04 ± 1.4 E-04 |
Acetate | 5.9 E-04 ± 1.3 E-04 | 8.3 E-04** ± 1.7 E-04 | 4.9 E-04 ± 2.3 E-04 | 5.8 E-04 ± 2.5 E-04 | 6.1 E-04 ± 1.3 E-04 | 4.3 E-04* ± 2.3 E-04 |
Adenine | 3.3 E-04 ± 1.5 E-04 | 3.0 E-04 ± 1.6 E-04 | 1.6 E-04 ± 9.7 E-05 | 1.9 E-04 ± 1.0 E-04 | 3.0 E-04 ± 4.5 E-05 | 1.6 E-04** ± 1.2 E-04 |
Alanine | 2.0 E-03 ± 4.9 E-04 | 1.4 E-03** ± 4.2 E-04 | 1.8 E-03 ± 8.8 E-04 | 1.4 E-03 ± 4.6 E-04 | 2.4 E-03 ± 2.8 E-04 | 1.5 E-03** ± 7.2 E-04 |
Ascorbate | 1.2 E-03 ± 3.7 E-04 | 7.7 E-04** ± 3.5 E-04 | 9.2 E-04 ± 5.0 E-04 | 7.2 E-04 ± 3.2 E-04 | 1.2 E-03 ± 2.5 E-04 | 8.2 E-04* ± 4.1 E-04 |
Carnitine | 5.7 E-04 ± 3.2 E-04 | 5.8 E-04 ± 3.5 E-04 | 6.4 E-04 ± 3.5 E-04 | 9.7 E-04* ± 4.3 E-04 | 7.0 E-04 ± 2.6 E-04 | 7.1 E-04 ± 3.8 E-04 |
Choline/Acetylcholine/Phosphocholine | 6.0 E-04 ± 3.0 E-04 | 8.8 E-04 ± 6.6 E-04 | 4.6 E-04 ± 3.6 E-04 | 5.4 E-04 ± 2.7 E-04 | 6.2 E-04 ± 2.6 E-04 | 3.4 E-04* ± 2.3 E-04 |
Citrate | 3.6 E-04 ± 1.2 E-04 | 2.6 E-04 ± 1.3 E-04 | 3.2 E-04 ± 1.4 E-04 | 2.5 E-04 ± 1.1 E-04 | 4.9 E-04 ± 1.2 E-04 | 2.9 E-04** ± 1.8 E-04 |
Creatine/Creatine phosphate | 1.7 E-03 ± 5.2 E-04 | 2.6 E-03** ± 7.2 E-04 | 1.5 E-03 ± 6.8 E-04 | 1.8 E-03 ± 8.3 E-04 | 1.6 E-03 ± 3.3 E-04 | 1.7 E-03 ± 1.0 E-03 |
Formate | 1.2 E-04 ± 7.6 E-05 | 1.3 E-04 ± 5.6 E-05 | 3.9 E-05 ± 3.4 E-05 | 5.0 E-05 ± 5.0 E-05 | 1.2 E-04 ± 5.6 E-05 | 4.8 E-05** ± 2.5 E-05 |
Glutathione | 2.5 E-03 ± 7.4 E-04 | 1.2 E-03** ± 4.3 E-04 | 2.2 E-03 ± 1.4 E-03 | 1.5 E-03 ± 6.4 E-04 | 2.5 E-03 ± 4.8 E-04 | 1.9 E-03 ± 1.3 E-03 |
Lactate | 2.3 E-02 ± 4.4 E-03 | 2.0 E-02*± 3.0 E-03 | 1.7 E-02 ± 7.8 E-03 | 1.5 E-02± 5.3 E-03 | 2.1 E-02 ± 2.7 E-03 | 1.5 E-02** ± 5.3 E-03 |
Sarcosine | 2.5 E-05 ± 1.1 E-05 | 6.6 E-05* ± 4.7 E-05 | 1.9 E-05 ± 9.9 E-06 | 5.0 E-05** ± 3.3 E-05 | 2.5 E-05 ± 9.9 E-06 | 2.8 E-05± 1.9 E-05 |
Succinate | 1.9 E-03 ± 7.0 E-04 | 1.1 E-03* ± 7.4 E-04 | 1.4 E-03 ± 9.4 E-04 | 1.0 E-03 ± 5.2 E-04 | 1.6 E-03 ± 6.4 E-04 | 1.4 E-03 ± 6.2 E-04 |
UDP-glucose/UDP-glucoronate | 2.4 E-04 ± 6.0 E-05 | 1.7 E-04* ± 6.7 E-05 | 1.8 E-04 ± 8.4 E-05 | 2.0 E-04 ± 8.6 E-05 | 1.8 E-04 ± 4.4 E-05 | 1.4 E-04* ± 5.2 E-05 |
Average concentration (mmol/g tissue) and standard deviation are shown for each experimental group.
Key: *p < 0.05 when compared with growth groups of the same breed; **p < 0.01 when compared with growth groups of the same breed.