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. Author manuscript; available in PMC: 2016 Dec 14.
Published in final edited form as: Protein J. 2016 Feb;35(1):1–16. doi: 10.1007/s10930-015-9641-y

Figure 8. Up- and downstream regulation of prohibitin network.

Figure 8

Prohibitin bindings and up/down stream regulations are shown. Basic amino acids of N-terminus may catalyze PI3K pathway by PIP3 binging, whereas C-terminus cardiolipin binding may have a role as an anti-apoptotic signaling by mtDNA binding.