Table 1. Demographic Characteristics of the NIA-LOAD Data Set.
| Characteristic | No. (%) of Participantsa | |
|---|---|---|
| Clinical Sample (n = 6553) | Genetic Sample (n = 2567) | |
| No. of participating study centers | 23 | 23 |
| Female sex | 4044 (61.7) | 1543 (60.1) |
| Age, mean (SD), y | 77.0 (9.0) | 76.6 (9.0) |
| Educational level, mean (SD), y | 11.6 (5.0) | 13.8 (3.0) |
| APOE ε4 allele | 3059 (52.6) | 1336 (52.0) |
| LOAD | 3468 (52.9) | 1243 (48.4) |
| Hypertension | 3086 (52.6) | 1209 (47.1) |
| T2D | 826 (14.1) | 278 (10.8) |
| Heart disease | 1280 (22.1) | 621 (24.2) |
| Stroke | 566 (9.6) | 220 (8.6) |
Abbreviations: APOE, apolipoprotein E; LOAD, late-onset Alzheimer disease; NIA-LOAD, National Institute on Aging Late-Onset Alzheimer Disease family study; T2D, type 2 diabetes.
a
Percentages have been weighted.