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. 2016 Sep 22;5(11):1620–1624. doi: 10.1242/bio.020966

Fig. 2.

Fig. 2.

Gbx2 and Otx2 are required for the correct assembly of otic and lens placodes. (A-H) Expression of Pax2 (A,B), Gbx2 (C,D), Foxe3 (E,F) and Otx2 (G,H) at the stages indicated at the top of the panels. (I,J) Pax2 expression in embryos with PPR grafts injected with Gbx2-EnR-GR mRNA in the absence (I) and presence of DEX (J). (K-N) Embryos with PPR grafts expressing Gbx2-EnR-GR and nuclear RFP at stage 18 (K,L) and cultured until stage 26 (M,N) embryos in the absence (K,M) or presence of DEX (L,N). (O,P) Intensity mapped overlays of 8 grafted embryos in the absence (O) and presence (P) of DEX. (Q,R) Embryos with PPR grafts injected with Otx2-EnR-GR mRNA in the absence (Q) and presence of DEX (R). (S-V) Embryos with PPR grafts expressing Otx2-EnR-GR and nuclear RFP at stage 26 (S,T) and cultured until stage 28 (U,V) in the absence (S,U) or presence of DEX (T,V). (W,X) Intensity mapped overlays of 8 grafted embryos in both the absence (W) and presence (X) of DEX.