Figure 4.

Sexually dimorphic inductions of inflammatory gene expression with advanced age across neural tissues. The inflammatory factors IL1α, IL1β, IL6, and TNFα demonstrated high levels of induction with aging, in many cases much higher in females than males. Y=Young, A=Adult, O=Old/Aged. Two-way analysis of variance (Age × Sex), **p < .01, ***p < .001 Age effect, ^## p < .01, ^### p < .001 Sex effect, ^p < .05, ^^^p < .001 interaction, Benjamini–Hochberg Multiple Testing Correction, n.s. not significant, n = 7–8/group (age/sex/region).