Table 3.
25(OH)D Status at 34 Weeks of Gestation According to Maternal Characteristics in Women Randomized to Placebo or Vitamin D Supplementation From 14 Weeks of Gestation
Placebo |
1000-IU/d Cholecalciferol |
|||
---|---|---|---|---|
β (95% CI) | P | β (95% CI) | P | |
Maternal age (y) | 0.67 (0.28, 1.07) | .001 | 0.70 (0.28, 1.11) | .001 |
Parity (yes vs no) | −1.25 (−5.69, 3.20) | .581 | −0.29 (−4.60, 4.03) | .896 |
Smoking at 34 weeks of gestation (yes vs no) | −13.45 (−22.12, −4.78) | .002 | −1.49 (−9.50, 6.52) | .715 |
Ethnicity (other vs White) | −8.69 (−18.59, 1.21) | .085 | 1.99 (−8.50, 12.48) | .709 |
Height (cm) | 0.15 (−0.19, 0.48) | .389 | −0.072 (−0.41, 0.27) | .675 |
BMI at 14 weeks of gestation (kg/m2) | −0.24 (−0.69, 0.20) | .284 | −0.47 (−0.90, −0.048) | .029 |
Weight at 34 weeks of gestation (kg) | −0.056 (−0.22, 0.11) | .492 | −0.23 (−0.38, −0.085) | .002 |
Weight gain early to late pregnancy (kg) | −0.23 (−0.85, 0.40) | .473 | −0.65 (−1.26, −0.039) | .037 |
Triceps SFT at 34 weeks of gestation (mm) | −0.059 (−0.38, 0.26) | .718 | −0.42 (−0.74, −0.10) | .010 |
Moderate/strenuous exercise in late pregnancy (h/wk) | 1.36 (−1.75, 4.47) | .389 | −0.76 (−3.63, 2.10) | .600 |
25(OH)D at 14 weeks of gestation (nmol/L) | 0.52 (0.40, 0.64) | <.001 | 0.21 (0.089, 0.33) | .001 |
Season of delivery (summer vs winter) | 22.77 (19.05, 26.50) | <.001 | 10.09 (6.039, 14.15) | <.001 |
Compliance (%) | 0.23 (0.044, 0.42) | .016 | 0.39 (0.19, 0.59) | <.001 |
Shown as nmol/L change in 25(OH)D per unit predictor. Bold typeface highlights the findings that are statistically significant. SFT, skinfold thickness.