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. 2016 Oct 6;101(12):4984–4993. doi: 10.1210/jc.2016-2891

Table 2.

Bone Assessments

Months Vertebral Findings
DXA BMD Z Score Corrected
Disc Space Narrowing
Wedging
Compression
Irregularity
Lumbara
Whole Bodyb
AI GH AI/GH AI GH AI/GH AI GH AI/GH AI GH AI/GH AI GH AI/GH AI GH AI/GH
0 2 3 4 2 0 1 0 0 4 1 1 0 0.372 ± .187 0.488 ± .320 0.569 ± .309 −0.328 ± .232 −0.464 ± .312 −0.062 ± .252
12 5 3 6 3 0 0 0 0 0 1 0 0 0.043 ± .181 0.243 ± .353 0.216 ± .312 −0.583 ± .195 −0.700 ± .309 −0.448 ± .281
24 3 2 6 2 0 0 0 0 0 1 0 1 −0.328 ± .227 0.243 ± .328 0.067 ± .306 −1.061 ± .313 −0.586 ± .244 −0.605 ± .257
a

P value of mean difference among groups for lumbar spine: 0 months, .99; 12 months, .52; 24 months, .03. Within-group changes over time: AI, < .001; GH, .04; AI/GH, .001. Baseline, n = 76; 12 months, n = 72; 24 months, n = 62.

b

P value of mean difference among groups: 0 months, .93; 12 months, .46; 24 months, .906. Within-group changes over time: AI, .003; GH, .06; AI/GH, <.001.