Skip to main content
. 2016 Dec 14;12(12):e1006084. doi: 10.1371/journal.ppat.1006084

Fig 4. The A. actinomycetemcomitans direct Fur regulon.

Fig 4

(A) Sequence logo representation of the Fur binding motif generated from all Fur-bound promoters (False Discovery Rate < 0.1) as outlined in Materials and Methods. The height of each base represents its frequency of occurrence. (B) Cellular processes directly regulated by Fur. Each process is encoded by a gene(s) whose promoter is bound by Fur. Shaded numbers above each process indicate fold enrichment of the ChIP to input DNA signal. 1.5–2.0 fold, light shade; >2.0–4.0 fold, medium shade; >4.0 fold, dark shade. Colored boxes below each process indicate transcriptional regulation by iron (blue or orange), Fur (purple or green), or neither (gray). Act. Is activated, and rep. is repressed. Afu, characterized transporter; 3+ in circle, free ferric iron; 3+ in square, ferric iron siderophore; Hg, hemoglobin; Tf, transferrin; octagon, ferritin; DspB, Dispersin B; hairpin, sRNA; hairpin in gray oval, CRISPR inhibiting a phage at the cell surface; G3P, glycerol-3-phosphate; cAMP, cyclic AMP; Trp, tryptophan; Phe, phenylalanine; Tyr, tyrosine.