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. 2016 Dec 14;12(12):e1006032. doi: 10.1371/journal.ppat.1006032

Fig 9. Overexpression of bcl-2 rescues other myeloid cell types from L. pneumophila-induced cell death.

Fig 9

Caspase-activation is measured in BMDC from CD68(bcl2)tg mice and littermate controls after infection with L. pneumophila. A representative staining is shown in (A), and the amount of apoptotic cells is quantified in (B). Caspase-activation is measured in alveolar macrophages from CD68(bcl2)tg mice and littermate controls after infection with L. pneumophila. A representative staining is shown in (C), and the amount of apoptotic cells is quantified in (D). Caspase-activation is measured in neutrophils from CD68(bcl2)tg mice and littermate controls after infection with L. pneumophila. A representative staining is shown in (E), and the amount of apoptotic cells is quantified in (F). These data are representative of at least 3 independent experiments with n = 3–4 per experiment. The mean values are displayed. * denotes P value ≤ 0.05.