Table 5. Multivariate analyses with both models based on previously described parameters associated with relapse.

Parameter		Renal relapse
		Cox regression model		Fine & Gray’s model
		P Value	csHR (95% CI)	P Value	F&G HR (95% CI)
Serum creatinine
	≤ 100 μmol/L	-	1	-	1
	101–200 μmol/L	0.6	0.62 (0.12–3.33)	0.5	0.44 (0.05–3.62)
	>201 μmol/L	0.4	0.46 (0.08–2.65)	0.2	0.23 (0.02–2.61)
Diagnosisa		0.2	0.55 (0.20–1.51)	0.9	0.96 (0.24–3.87)
PR3-ANCAb		0.6	0.61 (0.09–4.22)	0.3	0.45 (0.10–2.03)
MPO-ANCAb		0.9	0.84 (0.14–5.07)	0.4	0.62 (0.21–1.79)
Histopathological class
	Focal	0.009	0.09 (0.02–0.55)	0.3	0.32 (0.04–2.28)
	Crescentic	0.006	0.21 (0.07–0.64)	0.2	0.46 (0.13–1.63)
	Mixed	0.06	0.26 (0.07–1.07)	0.7	0.73 (0.18–2.98)
	Sclerotic	-	1	-	1

Sample size: 112 patients

Abbreviations: 95% CI, 95% confidence interval; ANCA, anti-neutrophil cytoplasmic antibody; csHR, cause-specific hazard ratio; MPO, myeloperoxidase; NS, not significant; PR3, proteinase 3; F&G HR, Fine and Gray’s hazard ratio.

^aReference group: Granulomatosis with polyangiitis.

^bReference group: Negative.