Table 2. Association of serum-S1P levels with risk factors for atherosclerosis and comorbidities in atherosclerotic patients.
| Frequency (percentage) | S1P(1) without mean +/- SD | S1P(1) with mean +/- SD | significant (P<0.05) | |
|---|---|---|---|---|
| Hypertension | 30 | 0.730 +/- 0.265 | 0.670 +/- 0.265 | no |
| Hypercholesteremia | 42 | 0.716 +/- 0.268 | 0.647 +/- 0.261 | no |
| Obesity | 7 | 0.696 +/- 0.265 | 0.573 +/- 0.268 | no |
| Diabetes | 27 | 0.688 +/- 0.268 | 0.685 +/- 0.264 | no |
| Smoking | 55 | 0.695 +/- 0.220 | 0.681 +/- 0.299 | no |
| COPD | 8 | 0.682 +/- 0.024 | 0.742 +/- 0.072 | no |
| Kidney insufficiency | 8 | 0.691 +/- 0.268 | 0.642 +/- 0.245 | no |
| Arrhythmia | 11 | 0.700 +/- 0.268 | 0.590 +/- 0.227 | no |
For every risk factor or concomitant disease analyzed, medical records were used to classify patients (N = 132) into two groups (without and with the condition). For each group, serum-S1P concentrations pre-treatment are shown (mean +/- SD). Significance of differences between patients with or without the respective condition was tested by two-tailed T-test.
(1)S1P concentrations are [nmol/mL]; COPD = Chronic obstructive pulmonary disease.