Table 3. Young women- related oxylipins.
Compound | Δ | Precursor | Pathway | Tendency | Ratio | P | Q | Effect |
---|---|---|---|---|---|---|---|---|
DPA | ω3 | ALA | PUFA | YW>YM | 3.2 | *** | $ $ | Anti-hypertensive |
EPA | ω3 | ALA | PUFA | YW>YM | 3.5 | ** | $ | Anti-hypertensive |
AA | ω6 | - | PUFA | YW>YM | 5.1 | * | $ | |
11,12-EET | ω6 | AA | P450 | YW>YM | 2.4 | * | $ | Anti-hypertensive |
14-15-EET | ω6 | AA | P450/- | YW>YM | 3.0 | ** | $ | Anti-hypertensive |
5,6-EET | ω6 | AA | P450 | YW>YM | 3.9 | ** | $ | Anti-hypertensive |
15-HETE | ω6 | AA | - | YW>YM | 2.9 | ** | $ | inflammation |
Δ: The first double bond.
-: non-enzymatic.
YW: young women.
YM: young men.
The ratio represents the median ratio the values in young women to those in young men. ALA: linokenic acid.
*p < 0.05,
**p < 0.01,
***p < 0.001 by the Mann-Whitney U-test.
$q<0.05,
$ $q<0.01 by Benjamini-Hochberg procedure for FDR.