Table 4. Elderly women-related oxylipins.
Compound | Δ | Precursor | Pathway | Tendency | Ratio | P | Q | Effect |
---|---|---|---|---|---|---|---|---|
9-HOTrE | ω3 | ALA | 5-LOX | EW>EM | 2.2 | * | $ | Unknown |
EW>YW | 0.3 | ** | $ | |||||
9-HODE | ω6 | LA | 5-LOX | EW>EM | 2.1 | ** | $ | Oxidative stress marker |
9-KODE | ω6 | LA | 5-LOX | EW>EM | 2.7 | ** | $ | Oxidative stress marker |
2,3-d-8-i-PGF2α | ω6 | AA | - | EW>EM | 2.2 | ** | $ | Oxidative stress marker |
2,3-d-8-i-PGF2α 2,3-dinor-8-iso- PGF2α.
Δ: the first double bond.
-: non-enzymatic.
EW: elderly women.
EM: elderly men.
Ratio represents the median ratio of elderly women to elderly men.
ALA: linolenic acid.
*p< 0.05,
**p< 0.01 by the Mann-Whitney U-test.
$q<0.05 by Benjamini-Hochberg procedure for FDR.