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. 2016 Dec 3;5:e22429. doi: 10.7554/eLife.22429

Figure 1. Selective labeling of age-defined abDGCs with the optogenetic silencer ArchT using retrovirus.

Figure 1.

(A) The schematics of the retroviral vectors (LTR: long terminal repeats; ψ: psi virus packaging sequence). (B) ArchT-GFP fluorescence in labeled abDGCs in the DG of an adult mouse, examined at 60 days post-injection (dpi). (C) ArchT-GFP fluorescence in labeled abDGCs examined at (i) seven dpi, (ii) 14 dpi, (iii) 30 dpi, and (iv) eight months post-injection. (Scale bar, 20 µm; green: ArchT-GFP fluorescence; red: TO-PRO-3 nuclei stain.).

DOI: http://dx.doi.org/10.7554/eLife.22429.002