Table 4.
Grade 3 or 4 Treatment-Related ToxicitiesÂ
| N = 190 | G 3/4 n (%) | G3 n (%) | G4 n (%) |
|---|---|---|---|
| Leukopenia | 2 (1%) | 2 (1%) | 0 (0%) |
| Neutropenia | 22 (12%) | 13 (7%) | 9 (5%) |
| Thrombocytopenia | 11 (6%) | 9 (5%) | 2 (1%) |
| Anemia | 7 (4%) | 6 (3%) | 1 (1%) |
| Febrile Neutropenia | 8 (4%) | 6 (3%) | 2 (1%) |
| Nausea | 5 (3%) | 5 (3%) | 0 (0%) |
| Vomiting | 5 (3%) | 4 (2%) | 1 (1%) |
| Mucositis | 2 (1%) | 2 (1%) | 0 (0%) |
| Diarrhea | 5 (3%) | 5 (3%) | 0 (0%) |
| Peripheral Neuropathy | 3 (2%) | 3 (2%) | 0 (0%) |
| Fatigue | 2 (1%) | 2 (1%) | 0 (0%) |
| Other* | 9 (5%) | 9 (5%) | 0 (0%) |
Other: Hepatic/transaminase elevation (n=3), rash (n=2), hyponatremia (n=1), thrombosis (n=1), allergic reaction (n=1), dehydration (n=1)