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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Clin Cancer Res. 2016 Jun 14;23(3):649–657. doi: 10.1158/1078-0432.CCR-16-0162

Table 4.

Grade 3 or 4 Treatment-Related Toxicities 

N = 190 G 3/4 n (%) G3 n (%) G4 n (%)
Leukopenia 2 (1%) 2 (1%) 0 (0%)
Neutropenia 22 (12%) 13 (7%) 9 (5%)
Thrombocytopenia 11 (6%) 9 (5%) 2 (1%)
Anemia 7 (4%) 6 (3%) 1 (1%)
Febrile Neutropenia 8 (4%) 6 (3%) 2 (1%)
Nausea 5 (3%) 5 (3%) 0 (0%)
Vomiting 5 (3%) 4 (2%) 1 (1%)
Mucositis 2 (1%) 2 (1%) 0 (0%)
Diarrhea 5 (3%) 5 (3%) 0 (0%)
Peripheral Neuropathy 3 (2%) 3 (2%) 0 (0%)
Fatigue 2 (1%) 2 (1%) 0 (0%)
Other* 9 (5%) 9 (5%) 0 (0%)
*

Other: Hepatic/transaminase elevation (n=3), rash (n=2), hyponatremia (n=1), thrombosis (n=1), allergic reaction (n=1), dehydration (n=1)