. Author manuscript; available in PMC: 2018 Feb 1.

Published in final edited form as: J Diabetes Complications. 2016 Jun 14;31(2):369–374. doi: 10.1016/j.jdiacomp.2016.06.012

Table 3.

Participant characteristics stratified by the presence of early diabetic kidney disease.

Variables	Rapid GFR decline (>3 mL/min/1.73 m²/year)		p-values
	No (n = 375)	Yes (n = 144)
Age (years)	37 ± 9	34 ± 9	<0.0001
Duration (years)	24 ± 9	21 ± 8	0.003
HbA1c (%)	7.9 ± 1.1	8.0 ± 1.5	0.58
HbA1c (mmol/mol)	63 ± 12	64 ± 16	0.58
BMI (kg/m²)	26 ± 4	26 ± 5	0.69
ACEi/ARB (yes, %)	35 (133)	22 (32)	0.004
Adiponectin at baseline (μg/ml)	14.7 ± 7.9	17.0 ± 10.3	0.02
Adiponectin at 6-year follow-up (μg/ml)	14.9 ± 8.9	16.2 ± 10.8	0.15
CRP^* at baseline (mg/l)	2.5 (2.4–2.6)	2.7 (2.5–3.0)	0.10
AER^* at baseline (μg/min)	9 (8–11)	10 (8–13)	0.44
AER^* at 6-year follow-up (μg/min)	8 (7–9)	10 (7–13)	0.24
ACR^* at baseline (mg/g)	9 (8–10)	11 (9–15)	0.08
ACR^* at 6-year follow-up (mg/g)	8 (7–9)	10 (8–13)	0.07
eGFR by CKD-EPI creatinine (mL/min/1.73 m²)	98 ± 25	121 ± 20	<0.0001
eGFR by CKD-EPI creatinine at 6-year follow-up (mL/min/1.73 m²)	101 ± 21	91 ± 22	<0.0001

Includes only participants with complete eGFR at baseline and follow-up.

Geometric means ± 95% confidence interval.