Table 1.

Stern−Volmer quenching constants and binding parameters for CTX-M-15 and Cefotaxime/Streptomycin/Cefoxitin interactions.

	Ksv(M−1)	Kq(M−1s−1)	Ka(M−1)	n	R2
CTX-M-15+CTX	14.6 × 104	3.38 × 1013	0.297 × 104	0.633	0.995
CTX-M-15+CTX+FOX	3.2 × 104	0.74 × 1013	0.037 × 104	0.558	0.993
CTX-M-15+CTX+FOX+STR	2.8 × 104	0.64 × 1013	0.361 × 104	0.794	0.991
CTX-M-15+CTX+STR	1.2 × 104	0.278 × 1013	0.126 × 104	0.773	0.994
CTX-M-15+CTX+STR+FOX	3.2 × 104	0.742 × 1013	1.253 × 104	0.904	0.991
CTX-M-15+STR	4.4 × 104	1.02 × 1013	0.019 × 104	0.47	0.997
CTX-M-15+STR+CTX	8.2 × 104	1.902 × 1013	2.904 × 104	0.916	0.993
CTX-M-15+STR+FOX	2.5 × 104	0.58 × 1013	0.162 × 104	0.729	0.992
CTX-M-15+STR+FOX+CTX	4.2 × 104	0.974 × 1013	2.023 × 104	0.944	0.994

CTX, cefotaxime; STR, streptomycin; FOX, cefoxitin.