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. 2016 Dec 15;7:567. doi: 10.3389/fphys.2016.00567

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Copyright © 2016 Salhi, Hassel, Siddiqui, Brundage, Ziolo, Janssen, Davis and Biesiadecki.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Tn exchange into skinned cells is similar for all investigated TnI pseudo-phosphorylations. (A) Representative TnI Western blot of myocytes following exchange demonstrates a similar presence of the faster migrating exogenous human cardiac TnI compared to the slower migrating endogenous rat cardiac TnI in all Tn's investigated. (B) Densitometry analysis of Western blots demonstrates the average percent of each exchanged exogenous Tn is not different. Control; purified recombinant rat WT cardiac TnI.