Table 3.

Hemodynamics, serum creatinine, and fluid balance between two groups at 0, 24, 48, and 72 h after initiation of treatment.

Hemodynamic variable	ECVVH (n = 24)	non-ECVVH (n = 27)	P value
Norepinephrine dose (μg/kg/min)
0 h	0.41 ± 0.12	0.39 ± 0.10	0.52
24 h	0.35 ± 0.11	0.36 ± 0.09	0.72
48 h	0.21 ± 0.07	0.33 ± 0.08	<0.001
72 h	0.06 ± 0.03	0.15 ± 0.05	<0.001
Serum creatinine (mg/dL)
0 h	0.79 ± 0.23	0.82 ± 0.27	0.67
24 h	0.70 ± 0.21	0.86 ± 0.28	0.03
48 h	0.55 ± 0.18	1.11 ± 0.33	<0.001
72 h	0.54 ± 0.18	1.26 ± 0.41	<0.001
Fluid balance (mL)
0 h	1189.9 ± 146.5	1129.4 ± 139.9	0.14
24 h	304.8 ± 49.7	426.2 ± 50.6	<0.001
48 h	−509.5 ± 60.8	−300.3 ± 39.7	<0.001
72 h	−407.4 ± 55.8	−196.2 ± 17.8	<0.001
ITBVI (mL/m2)
0 h	623.3 ± 117.9	642.6 ± 87.0	0.52
24 h	981.7 ± 98.8	960.4 ± 112.4	0.48
48 h	971.7 ± 94.5	1023.0 ± 104.1	0.07
72 h	998.2 ± 125.6	951.8 ± 146.5	0.23
CI (L/min/m2)
0 h	5.7 ± 0.5	5.5 ± 0.9	0.34
24 h	5.1 ± 0.8	4.8 ± 1.4	0.36
48 h	4.3 ± 0.7	4.5 ± 1.1	0.45
72 h	4.4 ± 0.4	4.5 ± 0.7	0.54
MAP (mmHg)
0 h	75.2 ± 9.3	72.6 ± 10.4	0.35
24 h	83.6 ± 7.9	81.1 ± 9.8	0.48
48 h	89 ± 6.8	86.1 ± 8.1	0.18
72 h	88.1 ± 8.2	85.4 ± 7.4	0.22
SVRI (dyns·s/(cm5·m2))
0 h	1117 ± 383	1065 ± 482	0.67
24 h	1317 ± 309	1289 ± 360	0.77
48 h	1662 ± 274	1584 ± 267	0.31
72 h	1683 ± 224	1641 ± 282	0.56
EVLWI (mL/kg)
0 h	13.2 ± 2.8	12.8 ± 3.1	0.63
24 h	12.5 ± 3.4	12.7 ± 3.6	0.84
48 h	9.1 ± 2.5	11.0 ± 2.7	0.01
72 h	7.6 ± 2.8	9.4 ± 3.2	0.04

CI = cardiac index, ECVVH = early continuous venovenous hemofiltration, EVLWI = extravascular lung water index, ITBVI = intrathoracic blood volume index, MAP = mean arterial pressure, and SVRI = systemic vascular resistance index.