Table 16:

Costs Used in the Economic Model

Variable	Base-Case Value, $	Range, $	Distribution	Reference
Episode Costs
CoreValve (TAVI), procedure cost, and any procedure-related adverse-event costs	47,198	44,617–49,780	Gamma	Li et al, 201556
Bioprosthesis (SAVR) procedure cost, and any procedure-related adverse-event costs	40,132	35,007–45,258	Gamma
Major Stroke
Hospitalization costs	31,081	2,458–149,412	Gamma	Mittmann et al, 201257
Monthly follow-up costs in the first year	4,246	10–22,570	Gamma
Monthly follow-up costs in subsequent years	4,101	15–21,678	Gamma
Adverse Events
Monthly cost of treatment for major vascular complications	5,692	4,269–7,115	Gamma	Doble et al, 201339
Monthly cost of treatment of life-threatening or disabling bleeding	5,128	3,419–6,838	Gamma	Singh et al, 201358
Monthly cost of pacemaker implantation	13,894	10,420–17,367	Gamma	Doble et al, 201339
Outpatient visit costs for TAVI	264	198–325	Gamma	Reynolds et al, 201654
Outpatient visit costs for SAVR	210	158–263	Gamma	Reynolds et al, 201654

Abbreviations: SAVR, surgical aortic valve replacement; TAVI, transcatheter aortic valve implantation.