Table 6:
Functional Outcomes After TAVI or BAV in Patients Who Were Not Suitable Candidates for Cardiac Surgery: Intention-to-Treat Analysisa
| Author, Year | NYHA Functional Class I/II Among Survivors, % | Quality of Life, Mean (SD) | ||
|---|---|---|---|---|
| KCCQ Summary | SF-12 Physical | SF-12 Mental | ||
| Baseline | TAVI: 7.8 BAV: 6.1 P = .60 |
TAVI: 36.2 (20.5) BAV: 34.4 (20.1) P = .44 |
TAVI: 28.2 (7.7) BAV: 27.7 (6.9) P = .54 |
TAVI: 44.5 (12.2) BAV: 45.2 (11.0) P = .57 |
|
30 days Leon et al, 201019 Reynolds et al, 201124 Douglas et al, 201527 |
NA | TAVI: 61.6 (26.2) BAV: 49.2 (24.3) |
TAVI: 34.6 (10.3) BAV: 30.2 (7.3) |
TAVI: 47.9 (11.0) BAV: 48.5 (10.9) |
|
1 year Reynolds et al, 201124 Kapadia et al, 201425 Douglas et al, 201527 |
TAVI: 76.3 BAV: 50 P < .0001 |
TAVI: 69.4 (25.3) BAV: 47.0 (24.6) |
TAVI: 34.9 (11.1) BAV: 29.7 (8.5) |
TAVI: 53.3 (10.0) BAV: 46.6 (11.7) |
|
2 years Kapadia et al, 201425 Douglas et al, 201527 |
NA | NA | NA | NA |
|
3 years Kapadia et al, 201425 Douglas et al, 201527 |
TAVI: 70 BAV: 50 P = .24 |
NA | NA | NA |
|
5 years Kapadia et al, 201528 |
TAVI: 85.7 SAVR: 60 P = .53 |
NA | NA | NA |
Abbreviations: BAV, balloon aortic valvuloplasty; KCCQ, Kansas City Cardiomyopathy Questionnaire; NA, not available; NYHA, New York Heart Association; SF-12, 12-item Short Form questionnaire; SD, standard deviation; TAVI, transcatheter aortic valve implantation.
a
Echocardiographic data (aortic regurgitation) were based on as-treated analysis. Quality-of-life data were estimated using random-effect growth curve models as reported by the author.