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. 2016 Dec 15;7:1961. doi: 10.3389/fmicb.2016.01961

Table 3.

AUC, sensitivity, and specificity for ROC curves calculated at optimal cutoff for SERPINA3, APOC1, and CFLAR.

Significant proteins by comparison groups AUC 95% CI Sensitivity (%) Specificity (%) P-value Log2 FC
MPP vs. HC
APOC1 0.853 0.796–0.907 77.6 81.1 8.81E–18 0.56
SERPINA3 0.739 0.662–0.818 77.6 68.4 1.38E–7 −0.34
CFLAR 0.524 0.436–0.61 77.6 42.1 7.56 E–3 0.12
MPP vs. IDC
APOC1 0.882 0.834–0.93 77.6 85.3 1.37E–18 0.78
SERPINA3 0.643 0.558–0.735 72.9 65.3 2.15E–3 −0.33
CFLAR 0.647 0.55–0.733 81.2 50.7 1.54 E–3 −0.66
MPP vs. (HC + IDC)
APOC1 0.866 0.816–0.915 77.6 82.9 1.34E–26 0.55
SERPINA3 0.698 0.624–0.763 77.6 64.7 1.42E–6 −0.05
CFLAR 0.578 0.514–0.648 71.8 54.1 3.74 E–3 −0.64