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Blocking mPFC NR2B-NMDARs does not influence working memory in rats. A, C, Placements of cannulae in mPFC of each rat included in this experiment (schematic illustration modified from Paxinos and Watson, 2005). Intra-mPFC microinjections of NR2B-selective antagonists Ro 25 (n = 11; B) and ifenprodil (n = 9; D) did not influence DRT choice accuracy. Data are mean percentage correct choices (y-axis) ± SEM plotted as a function of delay (in seconds; x-axis) and dose (separate lines).
